Modeling therapeutic antibody-small molecule drug-drug interactions using a 3D perfusable human liver co-culture platform

نویسندگان

  • Thomas J. Long
  • Patrick A. Cosgrove
  • Robert T. Dunn
  • Donna B. Stolz
  • Hisham Hamadeh
  • Cynthia Afshari
  • Helen McBride
  • Linda G. Griffith
چکیده

Amgen, Inc. Comparative Biology and Safety Science Laboratory, Cambridge, MA 02142, USA: TJL Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA: TJL, LGG Amgen, Inc. Comparative Biology and Safety Science Laboratory, Thousand Oaks, CA 91320, USA: PC, RTD, HH, HM, CA Center for Gynepathology Research, Massachusetts Institute of Technology, Cambridge, MA 02139: LGG Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA 15261, USA: DBS Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA: DBS This article has not been copyedited and formatted. The final version may differ from this version. DMD Fast Forward. Published on September 12, 2016 as DOI: 10.1124/dmd.116.071456

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تاریخ انتشار 2016